The United Nations defines sustainable development as 'development that meets the needs of the present without compromising the ability of future generations to meet their own needs'. Sustainable development necessarily entails decoupling the consumption of resources from economic growth. Material flow accounts (MFA) shows the physical inputs of materials which enter the economic system and the outputs generated in terms of physical units. These accounts enable us to obtain a set of aggregate indicators on the use of natural resources, from which productivity indicators can be derived. The Statistical Institute of (---), is conducting a statistical project on the material flow accounts with the aim of facilitating a detailed description of the interactions between the economy and the environment, providing information on the sustainability of our economic model in accordance with the harmonized methodology defined by Eurostat, adapted to the regional scope (NUTS 2). This project is also justified by the need for data and indicators derived from the circular economy policies for which the MFA is a fundamental pillar. The Regional Government’s 2017 approval of the drawing up of the National Plan for the implementation of the 2030 Agenda for sustainable development and the National Pact for Industry, which has an axis devoted to sustainability and the circular economy, have helped to promote the project. The Statistical Institute of (---) also forms part of the working group of the CITE (Interterritorial Statistics Committee) on indicators of the 2030 Agenda for sustainable development, with the purpose of exchanging methodological experiences on the preparation of the SDGs, and is establishing synergies with a technology centre in relation to the UrbanWINS project and promoting the integration of these results into an articulated information system, in cooperation with entities linked to the management of environmental and sustainability policies. This paper addresses the methodological adaptations which have been necessary and the limitations currently detected. It also outlines the guidelines for the future development of this module for environmental accounting in official regional statistics.