17:00 - 19:00
Fri-S9
Olfactory plasticity in a clinical context
Goethe Hall
Chair/s:
Thomas Hummel
The sense of smell is plastic. This plasticity is based on the regenerative capacity of the olfactory mucosa. The regeneration is the basis for recovery after olfactory loss which is especially significant since the SARS-CoV-2 pandemic. In COVID19 the virus attacks the olfactory mucosa and olfactory receptor neurons are destroyed during the process of the disease. During recovery, ORNs are regrown from the globose basal cells. In addition to these changes at a peripheral level, the volume of the olfactory bulb also changes in relation to olfactory function. The same has been shown for the primary and secondary olfactory cortex where also changes in functional responsiveness have been observed. It appears that the effectiveness of “olfactory training” is based on these effects.
Aim of the symposium is to highlight these plastic changes at several levels. To this end a group of excellent researchers will present work that touches upon several aspects of plasticity in the chemical senses. In terms of career levels the group is mixed, with a PhD student, four relatively young colleagues in their early career, and one established senior colleagues.
Because of the high significance of this topic in terms of recovery from COVID-19 associated olfactory loss we believe that it is highly attractive to ECRO participants!
Fri-S9-001
Regeneration of the olfactory mucosa
Bradley Goldstein

Department of Head and Neck Surgery and Communication Sciences, Department of Neurobiology, Duke University School of Medicine, Durham, NC, USA
Fri-S9-002
Changes in stem cell proliferation and receptor expression profile in response to odor exposure
Vittoria Avaro 1, Thomas Hummel 2, Federico Calegari 1

1 Centre for Regenerative Therapies Dresden (CRTD), TU Dresden, Fetscherstrasse 105, 01307 Dresden, Germany, 2 Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
Fri-S9-003
Central-nervous changes during olfactory recovery in Covid-19?
Sanne Boesveldt, Birgit van Dijk, Paul Smeets, Elbrich Postma

Sensory science and Eating behavior group, division of Human Nutrition and Health, Wageningen University, The Netherlands
Fri-S9-004
Compensation of sensory loss and effects of olfactory training on chemosensory and cognitive function
Anna Oleszkiewicz

Smell and Taste Clinic, TU Dresden, Institute of Psychology, University of Wroclaw
Fri-S9-005
Supersmellers! What are they? How could we become one?
Katherine L. Whitcroft

NHS – Pinderfields Hospital South Yorkshire, Centre for Olfactory Research Applications, Institute of Philosophy, School of Advanced Study, London, UCL Ear Institute, London, Smell and Taste Lab, TU Dresden
Fri-S9-006
Exploitation of brain plasticity using olfactory implants and transplants
Susanne Menzel, Thomas Hummel

Smell & Taste Clinic, Department of Otorhinolaryngology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.