19:10 - 21:00
Poster Session 13 “Development and function of Macrophage and DC”
Room: Ishikawa Ongakudō Interchange Hall
Poster Session
Mo-P13-1
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
Nikaïa Smith1, 2, Nicolas Pietrancosta1, Sophia Davidson3, Jacques Dutrieux4, Jan Münch2, Andreas Wack3, Sébastien Nisole5, Jean-Philippe Herbeuval1
1CNRS-UMR8601 - Team CBMIT - Université Paris Descartes, 45 Rue des Saints Pères, France, 2Institute of Molecular Virology - Ulm University Medical Center, Ulm, Germany, 3Immunoregulation Laboratory, Francis Crick Institute, London, United Kingdom, 4INSERM UMR-S 1124, Université Paris Descartes, Paris, France, 5Institut de Recherche en Infectiologie de Montpellier (IRIM) CNRS UMR 9004 - Montpellier University, Montpellier, France
Mo-P13-2
Effect of high glucose on human alveolar macrophages phenotype and phagocytosis of mycobacteria
Jorge Cervantes1, Jesse Vance1, Laura Sadofsky2, 3, Alyn Morice3
1Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, U.S.A., El Paso, United States, 2School of Biological, Biomedical and Environmental Sciences, University of Hull, Hull, U.K., Hull, United Kingdom, 3The Hull York Medical School, University of Hull, Hull, U.K., Hull, United Kingdom
Mo-P13-3
Induction of live cell phagocytosis by a specific combination of inflammatory stimuli
Takamasa Ishidome1, 2, Rikinari Hanayama1, 2
1Department of Immunologty, Kanazawa University Graduate School of Medicine, Takaramachi, Japan, 2Laboratory of Immune Network, Immunology Frontier Research Center (IFReC), Osaka University, Yamadaoka, Japan
Mo-P13-4
The recruited CCR2-expressing alveolar macrophages under the guidance of interstitial macrophage-derived CCL2 drive hepatocellular carcinoma lung metastasis by generating leukotriene B4.
Takuto Nosaka1, 2, Tomohisa Baba2, Yamato Tanabe2, Soichiro Sasaki2, Makoto Arita3, Yasunari Nakamoto1, Naofumi Mukaida2
1Second Department of Internal Medicine, Faculty of Medical Sciences, Fukui University, Yoshida-gun, Japan, 2Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan, 3Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
Mo-P13-5
Pirfenidone prevents and reverses lipotoxicity-induced hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages
Guanliang Chen1, Yinhua Ni1, Naoto Nagata1, Liang Xu1, Mayumi Nagashimada1, Shuichi Kaneko1, Tsuguhito Ota1, 2
1Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Japan, 2Division of Metabolism and Biosystemic Science, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, Japan
Mo-P13-6
Identification of Flt3-ligand producing cells by generating Flt3-ligand mCherry reporter mouse.
Nobuyuki Onai1, 2, Toshiaki Ohteki2
1Department of Immunology, Kanazawa Medical University, Ishikawa, Japan, 2Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
Mo-P13-7
The origin of osteoclasts in pannus in arthritis
Tetsuo Hasegawa1, 2, Junichi Kikuta1, Masaru Ishi1
1Osaka University, Osaka, Japan, 2Keio University, Tokyo, Japan
Mo-P13-8
Spred-2 protects mice from ConA-induced liver injury
Cuiming Sun, Teizo Yoshimura, Masatoshi Fujisawa, Toshiaki Ohara, Xu Yang, Akihiro Matsukawa
Department of Pathology and Experimental Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Mo-P13-9
Identification of a functional and transcriptional signature for tumor-infiltrating dendritic cells in mouse
Satoshi Ueha1, Haru Ogiwara1, Shigeyuki Shichino1, Jun Abe1, 2, Francis HW Shand1, Shinichi Hashimoto1, 3, Kouji Matsuhsima1
1Department of Molecular Preventive Medicine, The University of Tokyo, Tokyo, Japan, 2Theodor Kocher Institute, University of Bern, Bern, Switzerland, 3Department of Laboratory Medicine, Kanazawa University, Kanazawa, Japan
Mo-P13-10
CLEC5A is a critical receptor in innate immunity against bacteria infection
Szu-Ting Chen1, Fei-Ju Li1, Shie-Liang Hsieh2
1National Ynag-Ming University, Taipei, Taiwan, 2Acdemia Sinica, Taipei, Taiwan
Mo-P13-11
Monocyte maturation stage determines preferential recruitment to solid tumors in mice
Francis HW Shand1, Suang S Koid1, 2, Satoshi Ueha1, Kouji Matsushima1
1Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2Department of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan
Mo-P13-12
Cohesive transcriptional regulation plays critical role in CD4+ dendritic cell development 
Prafullakumar Tailor1, Irene Saha1, Hemant Jaiswal1, Jaring Schreuder2, Monika kaushik1, Shalin Naik2, Kuldeep Singh Chauhan1
1Laboratory of Innate Immunity, National Institute of Immunology (NII), New Delhi, India, 2Molecular Medicine Division, Walter and Eliza Hall Institute of Medical Research (WEHI), Parkville, Australia
Mo-P13-13
Immunization induces migration of MHC class II intermediate dendritic cells from immunized sites to draining lymph nodes.
Taiki Moriya1, Ryoyo Ikebuchi1, 2, Mizuki Ueda1, Yutaka Kusumoto1, Michio Tomura1
1Laboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan, 2Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan
Mo-P13-14
IFN-α inducible dendritic cells matured with OK-432 exhibit professional antigen-presentation and anti-tumor activity
Terutsugu Koya1, Shigetaka Shimodaira1, 2
1Department of Regenerative Medicine, Kanazawa Medical University, Uchinada, Japan, 2Center for Advanced Cell Therapy, Shinshu University Hospital, Matsumoto, Japan
Mo-P13-15
Blimp-1 is required for IFN-I production in plasmacytoid dendritic cells
Kuo-I Lin, Yi-An Ko
Genomics Research Center, Academia Sinica, Taipei, Taiwan
Mo-P13-16
Increased expression of BAFF receptor on monocytes is a contributory factor of IgG overproduction in patients with primary Sjögren's syndrome.
Keiko Yoshimoto, Katsuya Suzuki, Tsutomu Takeuchi
Keio University School of Medicine, Tokyo, Japan
Mo-P13-17
Involvement of Hexokinase 2  in autophagy dependent monocyte differentiation
Ellora SEN, Ankita Singh
National Brain Research Centre, Manesar, India
Mo-P13-18
Serum CC-chemokine ligand 18 level reflects disease activity, but not allergic manifestations of IgG4-related disease
Mitsuhiro Akiyama, Hidekata Yasuoka, Keiko Yoshimoto, Tsutomu Takeuchi
Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, Tokyo, Japan
Mo-P13-19
Unique and Overlapping Actions of Type I and III IFNs in Influenza A Virus Infection and Implications for Therapy.
Sophia Davidson1, 2, Teresa M McCabe2, Stefania Crotta2, Hans Henrik Gad3, Rune Hartmann3, Edith M Hessel4, Soren Beinke4, Andreas Wack2
1Division of Inflammation, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia, 2Immunoregulation Laboratory, Francis Crick Institute, London, United Kingdom, 3Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark, 4Refractory Respiratory Inflammation Discovery Performance Unit, Respiratory Therapy Area, GSK, Stevenage, United Kingdom
Mo-P13-20
Change in intestinal macrophages subset expressing α7nACh receptor during inflammation
Taiki Mihara, Juri Nakashima, Noriyuki Kaji, Hiroshi Ozaki, Masatoshi Hori
Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo, Japan
Mo-P13-21
Prognostic value of diametrically polarized tumor-associated macrophages in multiple myeloma
Xinyi Chen1, Jin Chen2, Wenyan Zhang3, Ruixue Sun1, Ting Liu1, Yuhuan Zheng1, Yu Wu1
1Department of Hematology and Hematology Research Laboratory, West China Hospital, Sichuan University, 37# Guoxue Xiang, 610041, Chengdu, Sichuan Province, China., Chengdu, China, 2Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China, 3Department of Pathology, West China Hospital, Sichuan University, Chengdu, China
Mo-P13-22
  CD11b+Gr1dim Tolerogenic Dendritic Cell-like Cells are Expanded in Interstitial Lung Disease in SKG Mice
Sho Sendo, Jun Saegusa, Hirotaka Yamada, Yoshihide Ichise, Ikuko Naka, Takaichi Okano, Soshi Takahashi, Yo Ueda, Kengo Akashi, Akio Morinobu
Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe City, Japan
Mo-P13-23
Regulation of inflammatory cytokine expression and osteoclastgenesis by gap junctional protein in vitro and in vivo.
Seiji Shimomura1, Shinji Tsuchida1, Yuji Arai2, Shuji Nakagawa2, Hiroaki Inoue1, Shohei Ichimaru1, Yuta Fujii1, Osam Mazda3, Toshikazu Kubo1
1Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, 21) Department of Sports and Para-Sports Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, 3Department of Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
Mo-P13-24
Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation
Kyoko Komai, Akihiko Yoshimura
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Mo-P13-25
Folate deficiency or leptin may exacerbate the inflammatory activity of LPS-induced RAW264.7 macrophages
Chun-Wai Chan, Bi-Fong Lin
Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan
Mo-P13-26
Absence of CCR5 axis inhibits thrombus resolution through reduced uPA, tPA and VEGF expression in murine DVT model
Mizuho Nosaka1, Yuko Ishida1, Akihiko Kimura1, Hiroki Yamamoto1, Yumi Kuninaka1, Emi Shimada1, Naofumi Mukaida2, Toshikazu Kondo1
1Department of Forensic Medicine, Wakayama Medical University, Wakayama, Japan, 2Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan
Mo-P13-27
Characteristics and functional regulation of dendritic cells in hepatitis B patients
Atsushi Yonejima, Eishiro Mizukoshi, Noriho Iida, Masaaki Kitahara, Masao Honda, Shuichi Kaneko
Department of Gastroenterology, Kanazawa University Hospital, Kanazawa, Japan
Mo-P13-28
The absence of CCL3 exaggerated CaCl2-induced aortic aneurysm
yuko ishida1, yumi kuninaka1, mizuho nosaka1, akihiko kimura1, naofumi mukaida2, toshikazu kondo1
1department of forensic medicine, wakayama medical university, wakayama, Japan, 2Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, kanazawa, Japan
Mo-P13-29
JAK/STAT guarantees robust differentiation of neural stem cells by shutting off biological noises in the developing fly brain
Makoto Sato1, Tetsuo Yasugi1, Yoshitaro Tanaka2, Masaharu Nagayama2, Shin-Ichiro Ei2
1Kanazawa University, Kanazawa, Japan, 2Hokkaido University, Sapporo, Japan
Mo-P13-30
Structural characterization of the chemokine receptor-binding protein, R1-15
Hiroko Takasaki1, Sosuke Yoshinaga1, Soichiro Ezaki1, Mitsuhiro Takeda1, Yuya Terashima2, Etsuko Toda2, Kouji Matsushima2, Hiroaki Terasawa1
1Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 2Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Mo-P13-31
CD206 positive intestinal macrophages contribute to the colonic epithelial wound healing
Shusaku Hayashi1, Mizuki Sendo1, Ai Hertati1, Kazuyuki Tobe2, Makoto Kadowaki1
1Division of Gastrointestinal Pathophysiology, Institute of Natural Medicine, University of Toyama, Toyama, Japan, 2First Department of Internal Medicine, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, Toyama, Japan
Mo-P13-32
Phenotypic conversion of the colon CD169+ macrophages by c-Maf.
Kenta Kikuchi, Masato Tanaka, Kenichi Asano
Laboratory of Immune Regulation, The School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
Mo-P13-33
IL-6 contributes to the interaction between enteric nervous system and mucosal immune system.
Hanako Ogata, Makoto Kadowaki, Takeshi Yamamoto
Division of Gastrointestinal Pathophysiology, Institute of Natural Medicine, University of Toyama, Toyama, Japan