A growing number of academics and development organizations are engaging in collaborative research projects. Increasingly, this includes efforts to co-produce research, rather than simply share information. These new ways of doing research raise important ethical and practical issues that are rarely discussed but deserve attention – especially in Africa. The continent is the region of the world in which these new approaches are particularly prevalent, and one where the challenges those approaches create tend to manifest in distinct or acute ways. In this paper, we draw on a collaborative research project with the Westminster Foundation for Democracy to illuminate these difficulties. We also offer suggestions for how to manage the challenges that arise when academics and development organizations conduct research together. Ensuring that such collaborations are both effective and ethical is not easy, but it must be done if we are to develop better informed policy and scholarship.