Autonomous vehicles are expected to provide many benefits, an increased productivity of the drivers being one of them. Drivers who are released from engaging in actions associated with driving may engage in productive activities en route such as reading and writing. In this case, however, motion sickness may become even more of a problem than it currently is due to the desynchronization of the visual, vestibular and somatosensory stimulation. Smyth et al. (2021) reported the results of a study suggesting that working on visuospatial problems substantially reduces the susceptibility to motion sickness. If a simple visuospatial training would indeed prove to be effective at reducing motion sickness, then this would be very good news for people suffering from motion sickness and for manufacturers of future autonomous vehicles alike. Here we present a conceptual replication of that study using a much larger sample size than that of the original study. A 30-minute simulated drive in a virtual environment was used to induce motion sickness. During the subsequent 14 days, participants in the visuospatial-training group, but not participants in the no-training group, worked on visuospatial problems for 15 minutes a day, as in the original study. Participants then returned to the laboratory for their second 30-minute simulated drive. Motion sickness severity was substantially reduced from the first to the second drive, but the visuospatial training did not affect this reduction in motion sickness. We conclude that working on visuospatial problems does not reduce the susceptibility to motion sicknes.