Plasticity in the sensory systems is a well-established phenomenon. For instance, plasticity in the visual system is reflected in the enhanced visual sensitivity of an eye that was previously visually deprived or received delayed or unreliable visual information. But does that also apply to the tactile sensory system? We hypothesized that unreliable tactile input provided to one hand should lead to enhanced tactile perception on that hand. To examine this, participants performed a brief tactile discrimination task with reference and test stimuli presented on their left and right index fingers, respectively. Following this initial baseline measure of tactile sensitivity, participants performed a 60-minute intervention, during which they built blocks using LEGO of different shapes and sizes with their right hand that was wearing a thick ski glove. Their left hand was bare and did not participate in the task. Immediately after this intervention, we re-tested tactile sensitivity at five consecutive time points. Our data showed enhanced tactile sensitivity during the first two minutes after the intervention; this effect vanished afterward. As we controlled for skin temperature we can rule out a potential influence. In sum, our findings suggest that the human tactile system has a considerable degree of plasticity following short exposure to unreliable tactile input, but unlike the visual system, this plasticity is rather short-lasting.