Social exclusion has been defined as the experience of being kept apart from others physically or emotionally. Over decades, a substantial body of experimental research has shown that people are negatively affected by emotional forms of exclusion (i.e., rejection or ostracism). Studies conducted during the COVID-19 pandemic further suggest that physical exclusion (i.e., a lack of physical contact) impairs well-being but that effects could depend on how socially included individuals feel. However, no experimental research has examined the effects of different combinations of the physical and social components of exclusion and how they might interact. Across two studies (N = 1,238), we manipulated both components separately via an imaginative scenario paradigm and measured their impact on established social exclusion outcomes (i.e., affect, needs, loneliness, prosocial and antisocial behavioral intentions). Effects of physical exclusion on emotional distress were dependent on individuals' social inclusionary status. Social inclusion was not able to eliminate negative effects of physical exclusion but to protect well-being to some degree compared to when individuals were physically and socially excluded. Social exclusion, irrespective of being paired with physical in- or exclusion, affected individuals most negatively. Physical and social exclusion lowered prosocial intentions independently from each other. For antisocial intentions, the physical component played a subordinate role: physical exclusion affected antisocial tendencies only under neutral social contact. Our findings add to a more nuanced understanding of social and physical aspects of exclusionary experiences.