When using simple levers, moving the to-be-controlled tip of the lever away or towards a target involves three different compatibility relationships: First, compatibility between the position of a stimulus and hand movement (i.e., stimulus-response [SR] compatibility). Second, compatibility between the position of the stimulus and the movement of the effective part of the tool (i.e., stimulus-effect [SE] compatibility). Third, compatibility between hand movement and the movement of the effective part of the tool (i.e., response-effect [RE] compatibility). An important question in this context concerns the importance of and potential interactions between each compatibility type. By using certain levers (i.e., “u-shaped” and “inverted-u-shaped” levers), and by letting participants either approach or avoid targets, Müsseler and Skottke (2011, Human Factors) tackled this question. They concluded that, with RE compatible tools, a compatible SR relationship is only beneficial when the SE relationship is compatible as well. When the SE relationship is incompatible, the incompatible SR relationship performs better than the compatible SR relationship. This interaction, however, was absent with a lever that involves an incompatible RE relationship. The present study first replicates the original study, as the original experiment employed a rather small sample of n = 10 with simple button presses. We present the results of our replication and further present and discuss experiments investigating the role of control input (e.g., by investigating continuous lever movements or touchless gestures).