15:45 - 17:15
Tue-P1
Room: Waalsprong 4
The effect of food and non-food odors on inhibitory control in obese and non-obese individuals
Tue-P1-041
Presented by: Javier Albayay
Javier Albayay 1, 2, Matilde Serini 2, Sofia Tagini 3, Federica Scarpina 3, 4, Alessandro Mauro 3, 4, Massimo Scacchi 5, 6, Umberto Castiello 2, Massimiliano Zampini 1
1 Center for Mind/Brain Sciences, University of Trento, Italy, 2 Department of General Psychology, University of Padova, Italy, 3 “Rita Levi Montalcini” Department of Neurosciences, University of Turin, 4 Istituto Auxologico Italiano, IRCCS, U.O. di Neurologia e Neuroriabilitazione, Ospedale San Giuseppe, Italy, 5 Istituto Auxologico Italiano, IRCCS, U.O. Medicina Generale, Ospedale San Giuseppe, Italy, 6 Department of Clinical Sciences and Community Health, University of Milan, Italy
Pleasant odor stimuli have been found to reduce response inhibition, which refers to the executive ability to withhold or cancel inappropriate actions, in healthy-weight individuals. However, the interaction between olfaction and inhibitory control in obesity remains understudied. Inhibitory control plays a crucial role in food-related behavior, and olfaction is one of the main sensory determinants for food intake. Here, we aim to determine if inhibitory control differs between individuals with obesity (BMI ≥ 30 kg/m2) and non-obese individuals (BMI range = 18-25 kg/m2) following the presentation of different odor stimuli related to edibility (food odors vs. non-food odors) and caloric density for food odors (high-calorie content vs. low-calorie content). The study is currently underway with 12 participants per group (expected n per group = 25), matched for age and sex. Participants performed a Go/No-Go task which included three isointense odor primes: orange (low-calorie food odor), cookie (high-calorie food odor) and lavender (non-food odor); clean air was used as a control. Mixed-effects models revealed that individuals with obesity exhibited reduced inhibitory control compared to non-obese individuals, as indicated by higher No-Go error rates (p<0.001). Odor presentation resulted in faster Go responses (p<0.001) and higher No-Go error rates (p=0.006), indicating reduced inhibitory control compared to the control condition. These effects were more pronounced for food (vs. non-food) odors in both groups (ps<0.001). Furthermore, the high-calorie (vs. low-calorie) food odor triggered faster Go responses and higher No-Go error rates only in individuals with obesity (p=0.013). This study adds to the current understanding of the effects of odor stimuli on goal-directed behavior, emphasizing the influence of odor edibility, weight status, and their interaction on response inhibition and readiness. This work was supported by the “COG19” project (grant number 40900003).