15:20 - 16:50
Workshop 8, “Cytokines and inflammatory factors in host defense”
Room: ANA Crowne Plaza “Ohtori” Room A
Workshop Session
Chair/s:
Christopher Hunter, Reiko Shinkura
15:20 - 15:40
Tu-WS8-1
High-affinity monoclonal IgA derived from mouse Intestine as a modulator of the gut microbiota
Reiko Shinkura
Nara Institute of Science and Technology, Nara, Japan
15:40 - 15:50
Tu-WS8-2
Antibiotics disrupt intestinal macrophage homeostasis to induce long-lived inflammatory T-cell responses and defective protection against bacterial and parasitic infections.
Elizabeth Rebecca Mann1, 2, Peter Andersen3, Cristina Alcon-Giner4, Charlotte Leclaire4, Shabhonam Caim4, Hannah Wessel1, Allison Bancroft2, Alberto Bravo-Blas1, Verena Kästele1, Daniel Peterson3, 5, Richard Grencis2, Xuhang Li3, Allan Mowat1, Lindsay Hall4, Mark Travis2, Simon Milling1
1University of Glasgow, Glasgow, United Kingdom, 2University of Manchester, Manchester, United Kingdom, 3Johns Hopkins Medicine, Baltimore, United States, 4Quadrate Institute Bioscience, Norwich, United Kingdom, 5Eli Lilly Research Laboratories, Indianapolis, United States
15:50 - 16:00
Tu-WS8-3
Osteoblasts mediate immunosuppression during sepsis by regulating lymphopoiesis
Asuka Terashima1, Kazuo Okamoto1, Tomoki Nakashima2, Koichi Ikuta3, Hiroshi Takayanagi4
1Department of Osteoimmunology, Graduate School of Medicine and Faculty of Medicine The University of Tokyo, Tokyo, Japan, 2Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 3Laboratory of Biological Protection, Department of Biological Responses, Institute for Virus Research, Kyoto University, Kyoto, Japan, 4Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo, Japan
16:00 - 16:10
Tu-WS8-4
IL-17A controls autoimmune disease by inhibiting the expression of IL-17 lineage cytokines through a negative feedback loop involving IL-24
Wai Po Chong1, 2, Kumarkrishna Raychaudhuri2, Reiko Horai2, Mary J Mattapallil2, Phyllis B Silver2, Yingyos Jittayasothorn2, Chi-Chao Chan2, Jun Chen1, Rachel Caspi2
1State Key Lab. Ophthalmol., Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China, 2Lab of Immunology, National Eye Institute, National Institutes of Health, Bethesda, United States
16:10 - 16:20
Tu-WS8-5
Non-linear scaling of CD8+ T cell responses by bystander DCs
Jun Abe1, Philipp Germann2, 3, Jorge Ripoll4, 5, James Sharpe2, 3, 6, Jens V Stein1
1Theodor Kocher Institute, University of Bern, Bern, Switzerland, 2EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain, 3Universitat Pompeu Fabra (UPF), Barcelona, Spain, 4Department of Bioengineering and Aerospace Engineering, Universidad Carlos III of Madrid, Madrid, Spain, 5Experimental Medicine and Surgery Unit, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón, Madrid, Spain, 6Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain
16:20 - 16:30
Tu-WS8-6
A Novel Role for Epstein-Barr Virus-Induced Gene 3 as An Intracellular Molecule That Enhances IL-23 Receptor Expression by Binding to Calnexin and IL-23 Receptor
Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto
Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan
16:30 - 16:50
Tu-WS8-7
The role of BATF-3 dependent DC in the formation of fat associated lympoid clusters
Christopher Hunter, David Christian
University of Pennsylvania, Philadelphia, United States