13:40 - 15:10
Workshop 1, ‟Innate immunity and infection”
Room: ANA Crowne Plaza “Ohtori” Room A
Workshop Session
Chair/s:
Mitsutoshi Yoneyama, Shinobu Saijo
13:40 - 13:50
Mo-WS1-1
Roles of cytokines in the anti-fungal immunity
Shinobu Saijo
Medical Mycology Research Center, Chiba University, Chiba, Japan
13:50 - 14:00
Mo-WS1-2
Pathogenic fungus, Trichophyton mentagrophytes negatively regulates host immune responses via Siglec receptors.
Yasunobu Miyake1, Eri Suematsu1, Shinobu Saijo2, Sho Yamasaki2, 3, 4, Hiroki Yoshida1
1Saga University, Faculty of Medicine, Saga, Japan, 2Chiba University, Medical Mycology Research Center, Chiba, Japan, 3Osaka University, Research Institute for Microbial Diseases, Osaka, Japan, 4Kyushu University, Medical Institute of Bioregulation, Fukuoka, Japan
14:00 - 14:10
Mo-WS1-3
Two distinct ITAM-coupled receptors recognize mycobacterial mycolic acid-containing lipids and differently regulate immune responses.
Ei'ichi Iizasa1, Takayuki Uematsu2, Yasushi Chuma3, Hideyasu Kiyohara3, Mio Kutobta4, Masayuki Umemura5, Goro Matsuzaki5, Sho Yamasaki6, Hiromitsu Hara1
1Department of Immunology, Division of Infection and Immunity, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, 2Research and Development Department, Japan BCG Laboratory, Tokyo, Japan, 3Division of Biomedical Laboratory, Department of Biomedical Research Kitasato University Medical Center, Saitama, Japan, 4Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan, 5Tropical Biosphere Research Center University of the Ryukyus, Naha, Japan, 6Department of Molecular Immunology, Division of Host Defense, Research Institute for Microbial Disease, Osaka University,, Osaka, Japan
14:10 - 14:20
Mo-WS1-4
Immune-modulating capacity of a plant-derived dsRNA and its potential applications
Takara Hajake1, 2, Dacquin Muhandwa Kasumba1, 2, Haruka Oda1, 2, Keita Matsuno3, Masatoshi Okamatsu4, Yoshihiro Sakoda3, 4, Hiroki Kato1, 2, Takashi Fujita1, 2
1Laboratory of Molecular Genetics, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2Laboratory of Molecular and Cellular Immunology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan, 3Global Station for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Japan, 4Laboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan
14:20 - 14:30
Mo-WS1-5
cGAS-STING signaling is required for host defense from WNV neuropathology
Kathryn McGuckin Wuertz1, 2, 4, 5, Emily A. Hemann2, 5, Courtney Wilkins2, 5, Jessica Snyder3, Piper M. Treuting3, Michael Gale Jr.1, 2, 5
1University of Washington, Department of Global Health, Seattle, WA, United States, 2University of Washington, Department of Immunology, Seattle, WA, United States, 3University of Washington, Department of Comparative Medicine, Seattle, WA, United States, 4Department of Defense; United States Army Medical Department, San Antonio, TX, United States, 5Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA, United States
14:30 - 14:40
Mo-WS1-6
Dengue virus degrades cGAS to prevent mitochondrial DNA sensing during infection
Sebastian Aguirre1, Priya Luthra6, Maria Teresa Sanchez1, 2, Ana Maria Maestre1, Tongtong Zhu1, 3, Jessica Pintado Silva1, 3, Laurece Webb1, 3, Dabeiba Bernal-Rubio1, Alexander Solovyov5, Benjamin Greenbaum5, Viviana Simon1, 2, 4, Christopher Basler6, Lubbertus Mulder1, 2, Adolfo Garcia-Sastre1, 2, 4, Ana Fernandez-Sesma1, 3, 4
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States, 2Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, United States, 3Graduate School of Biological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States, 4Department of Medicine, division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, United States, 5Tisch Cancer Institute, Division of Hematology and Medical Oncology, Department of Medicine, Department of Pathology, New York, United States, 6Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, United States
14:40 - 14:50
Mo-WS1-7
In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein
Christoph M. Deeg1, Ebrahim Hassan1, 2, 3, 4, Pascal Mutz1, Lara Rheinemann1, Veronika Götz1, Linda Magar1, Mirjam Schilling1, Carsten Kallfass1, Cindy Nürnberger1, 2, Sébastien Soubies1, Georg Kochs1, Otto Haller1, Martin Schwemmle1, Peter Staeheli1
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany, Freiburg, Germany, 2Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany, 3Microbiology Department, Faculty of Science, Ain Shams University, Cairo, Egypt, Cairo, Egypt, 4These authors contributed equally to this work, Freiburg, Germany
14:50 - 15:00
Mo-WS1-8
Targeting of viral replication complexes by LC3-guided interferon-inducible GTPases
Seungmin (Sam) Hwang1, 2, 3, Scott B. Biering2, Jayoung Choi1, Hailey M. Brown3
1The University of Chicago, Department of Pathology, Chicago, United States, 2The University of Chicago, Committee on Microbiology, Chicago, United States, 3The University of Chicago, Committee on Immunology, Chicago, United States
15:00 - 15:10
Mo-WS1-9
Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases.
Miwa Sasai1, 2, Masahiro Yamamoto1, 2
1Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan