Petasites japonicus Maxim is a perennial herb that belongs to the Compositae . The leaves or stalks of P. japonicus commonly comsumed as vegetable in Korea and Japan. Moreover, the aerial parts of P. japonicus has been used as a Japanese folk medicine for antitussive, antipyretic, or wound healing agent .[1] Phytochemical study on a hot water extract from the leaves of P. japonicus resulted in the isolation and characterization of a new lignan (1), along with two phenolic compounds (2 and 3) , three dicaffeoylquinic acid (4-6), and one phenylpropanoid (7) having previously known chemical structures. The structure of the new compound 1 was determined by interpretation of spectroscopic data, particularly by 1D- and 2D-NMR studies.
[1] Mizuno M., Tanaka T.. Nihon Yakuso Zensyo. Shin-Nihon-kouki: Tokyo; 1995: 557-559
