Patrinia scabra Bunge is a perennial herb that belongs to the Valerianaceae . The roots of P. scabra have been used as a traditional Chinese medicine to treat malaria, dysentery, leukemia, gastric cancer , typhoid fever, injuries from falls, and leucorrhoea.[1] Repeated chromatography of a 70% aqueous EtOH extract of the roots of P. scabra led to the isolation and characterization of t en new iridoids (1-10), along with two iridoids (11 and 12) and two lignans (13 and 14) having previously known chemical structures. The structures of the new compounds were determined by interpretation of spectroscopic data, particularly by 1D- and 2D-NMR studies.
[1] Editorial Board of Chinese Herbal, State Administration of Traditional Chinese Medicine, Chinese herbal: Shanghai Science and Technology Press; Shanghai, 1999: Vol. 7, 567.
