This study investigated whether domain-specific expertise moderates performance in a basketball-specific anticipation-response-inhibition (ARI) task. Participants with domain-specific basketball expertise, domain-specific handball expertise, and novices without domain-specific expertise were included. In the ARI task, a video of a basketball jump shot was viewed and participants were instructed to respond as precisely as possible at the moment the ball left the attacker’s fingertips (go-trials). When a simulated pump fake was viewed (stop-trials), however, participants were asked to inhibit their response. Inhibitory performance was quantified using the PNR, which indicates the point at which inhibition failed in 50 % of the trials. Response precision was assessed by using the constant error (CE). To account for strategic response delays favoring precision over inhibition, the corrected PNR was calculated by adding CE to the observed PNR. The results demonstrated that participants with domain-specific basketball expertise showed superior inhibitory control compared to those with domain-specific handball expertise and novices without domain-specific expertise, while no significant differences were observed between participants with handball expertise and novices. Additionally, strategic adjustments based on the preceding trial type were observed, as all participants (irrespective of expertise) delayed their responses in go trials following a stop trial, irrespective of whether the inhibition was successful or unsuccessful. Overall, the findings suggest that domain-specific basketball expertise enhances performance in the basketball-specific ARI task. The question if the expertise effects observed are restricted to the domain-specific task or reflect a generally enhanced inhibitory control cannot be answered and warrants further investigation.