Hungry glia cells modulate odor foraging and feeding
Thu-S4-005
Presented by: Ilona C. Grunwald Kadow
The main goal of my research is to understand how chemosensory information is translated into a state- and context-dependent percept of the environment guiding decisions and behavior. To this end, we combine novel methodology such as in vivo fast lightfield wholebrain calcium imaging of neurons and glia cells with (opto)genetic manipulations and behavioral analysis. We employ methods for large scale analysis of imaging and behavioral data with computational modelling and anatomy to unravel how neural circuits across the brain encode what the animal experiences and direct its next action. Most recently, we became interested in how cellular metabolism and energy state of neurons and glia cells relate to feeding and foraging behavior. In the meeting, I would like to discuss unpublished data suggesting that metabolic sensing of different types of glia cells shape foraging and feeding behavior. We hypothesize that similar basic metabolic pathways guide foraging behavior both in single cell organisms as well as in animals with highly complex brains.