Spatial transcriptomics enable the mapping of cell-type markers within tissues of interest, although limitations arise when cell-type transcriptional markers are expressed in relatively low abundance. Such an issue exists in mapping olfactory glomeruli, which are the fundamental units of the mammalian olfactory bulb and originate from axons from olfactory sensory neurons expressing the same olfactory receptor. We combine target capture enrichment sequencing to overcome low-abundance target expression with spatial sectioning along the anteroposterior, dorsoventral, and mediolateral axes to map 86% of olfactory receptors and generate a three-dimensional model of glomeruli positions on the murine olfactory bulb. Our dataset identifies a unique relationship between specific olfactory receptor residues and olfactory bulb target positions.