12:30 - 14:00
Poster viewing
Room: Galeries and Marie Curie
Clinical presentation and outcomes of Chronic Intestinal Pseudoobstruction in pediatric patients
Dayoung Ko, Jeik Byun, Hee-Beom Yang, Joong Kee Yoon, Hyun-young Kim, Sung Eun Jung
Seoul National University Children's Hospital

Introduction: Chronic intestinal pseudoobstruction (CIPO) presents symptoms of intestinal obstruction without any lesions occluding the intestine. It is a rare and difficult disease entity not diagnosis but also treatment. The standard diagnosis and management has not yet be established enough. In this study, we are aim to report clinical outcomes of pediatric intestinal pseudoobstruction and predictive factor for the poor outcomes.

Methods: We retrospectively reviewed the 76 patients who were diagnosed as a primary pediatric CIPO between January 1985 and December 2017 in one institute. Age at diagnosis ranged between 0 and 221 months (median 4 months). We categorized the clinical outcomes into four groups and evaluate clinical outcomes.

Results: A total of 75 patients underwent the operation including enterostomy, bowel resection and venting gastrostomy. In terms of histopathology, 56 patients were a neuropathy, 11 patients were a myopathy and 3 patients showed both results in specimen. In contrast, we could not abnormal finding of enteric neuron and muscle in specimen of six patients. The overall mortality of primary CIPO was 10.5% (8 of 76). Neuropathic type CIPO patients showed better prognosis than myopathic type patients in significant (p <0.008). Furthermore 41 patients and 21 patients categorized as a good and poor outcome group in respectively. The patients who experienced a home parenteral nutrition (PN) had tendency with poor clinical outcomes due to recurrent hospitalization.

Conclusion: In recent, the clinical outcome of CIPO improved because of an early diagnosis, proper surgical treatment and multidisciplinary management. In this study, we showed an acceptable clinical outcome even though many well-known morbidities.

Disclosure Statement

The authors have no conflicts of interest.


Session:
FAREWELL FESTIVE LUNCH & POSTER VIEWING
Presenter/s:
Dayoung Ko
Presentation type:
Poster only presentation
Room:
Galeries and Marie Curie
Date:
Saturday, July 6, 2019
Time:
12:30 - 14:00
Session times:
12:30 - 14:00