Study for the age-dependent difference of trans-epidermal water loss (TEWL) response to dry environment in Korean
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Presented by: Minyoul Chang
Our skin responds to changes in various environmental conditions to maintain internal homeostasis. Especially, the skin can be affected in big by environmental humidity, low humidity or high humidity. This study was designed to investigate the difference of skin’s responding properties to dry environment (low humidity) in young and old skin.
A total of 267 healthy Korea women and men aged between 20 and 57 years participated in the study (20s: 32, 30s: 58, 40s: 101, 50s: 76). The test conditions were adjusted to provide 20±2℃ of temperature and 20±5% of relative humidity(RH) for dry environment. The trans-epidermal water loss (TEWL) was measured on the ventral forearm before exposure and after exposure of 20 min to low RH. The statistical significance was determined at p<0.05.
Normal TEWL (data of before exposure to low RH) increased by 20s to 50s, and there was significant difference between (20s and 30s) and (40s and 50s) (p<0.05). The difference between normal TEWL and low RH TEWL (∆TEWL) decreased by 20s to 50s, and there was significant difference between (20s and 30s) and 50s (p<0.05).
As results, TEWL showed significant increase in their 40s and older and ∆TEWL showed significant decrease in their 50s. This means that young skin (20s and 30s) can show more dynamic response to dry environment (low RH) than 40s and older. And ∆TEWL may be a useful parameter to evaluate the skin’s adaptability to dry environment.
A total of 267 healthy Korea women and men aged between 20 and 57 years participated in the study (20s: 32, 30s: 58, 40s: 101, 50s: 76). The test conditions were adjusted to provide 20±2℃ of temperature and 20±5% of relative humidity(RH) for dry environment. The trans-epidermal water loss (TEWL) was measured on the ventral forearm before exposure and after exposure of 20 min to low RH. The statistical significance was determined at p<0.05.
Normal TEWL (data of before exposure to low RH) increased by 20s to 50s, and there was significant difference between (20s and 30s) and (40s and 50s) (p<0.05). The difference between normal TEWL and low RH TEWL (∆TEWL) decreased by 20s to 50s, and there was significant difference between (20s and 30s) and 50s (p<0.05).
As results, TEWL showed significant increase in their 40s and older and ∆TEWL showed significant decrease in their 50s. This means that young skin (20s and 30s) can show more dynamic response to dry environment (low RH) than 40s and older. And ∆TEWL may be a useful parameter to evaluate the skin’s adaptability to dry environment.