In vivo evaluation of the emotional status by direct skin measurement, as part of the study of an active formula vs placebo
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Presented by: Jean-Marie BOTTO
The well-being and well-feeling associated with looking healthy, feeling healthy, positive emotions and better aging is at the center of consumers preoccupations. Oxytocin, known as the “feel-good molecule” and the “love molecule”, participates to global well-being, being associated with positive social interactions, parental care, romantic attachment, love and with anti-aging properties. The human skin has acquired the ability to sense and produce oxytocin, and in coordination with the presence of mechanosensory nerve fibers, is at the center of well-being.
We have screened and developed an innovative botanical extract to balance these aspects in the skin. A clinical study was designed to evaluate various parameters on subjects applying on the face, a formulation containing a botanical extract vs placebo. The study enrolled 30 volunteers aged 36 to 66 yo. The volunteers were divided in two groups of 15 volunteers, homogeneous in age and gender. One group applied on the face a cream containing an exclusive botanical extract, and the other group applied a placebo cream, for 28 days, morning and evening. The well-being of volunteers was evaluated by three different methods: (1) WHO-5 Well-being Index, (2) measurement of the salivary oxytocin level, and (3) measurement of the emotional state of the volunteers by Emotion Capture© Technology. Moreover, skin relaxation and healthy glow effect were also evaluated by silicone replica image analysis and by measuring skin complexion.
The study revealed an improvement of the well-being and emotional status of the volunteers after 28 days of application of the formulated botanical extract, and that was not the case with the placebo. Besides, the enhancement of skin complexion and the decrease of the forehead surface roughness parameters were observed for the group applying the extract compared to the placebo group, suggesting a healthier skin complexion and a smoother and more relaxed skin.
Overall, this study tends to suggest a potential beneficial effect on the emotional and sensory aspects of skin physiology
We have screened and developed an innovative botanical extract to balance these aspects in the skin. A clinical study was designed to evaluate various parameters on subjects applying on the face, a formulation containing a botanical extract vs placebo. The study enrolled 30 volunteers aged 36 to 66 yo. The volunteers were divided in two groups of 15 volunteers, homogeneous in age and gender. One group applied on the face a cream containing an exclusive botanical extract, and the other group applied a placebo cream, for 28 days, morning and evening. The well-being of volunteers was evaluated by three different methods: (1) WHO-5 Well-being Index, (2) measurement of the salivary oxytocin level, and (3) measurement of the emotional state of the volunteers by Emotion Capture© Technology. Moreover, skin relaxation and healthy glow effect were also evaluated by silicone replica image analysis and by measuring skin complexion.
The study revealed an improvement of the well-being and emotional status of the volunteers after 28 days of application of the formulated botanical extract, and that was not the case with the placebo. Besides, the enhancement of skin complexion and the decrease of the forehead surface roughness parameters were observed for the group applying the extract compared to the placebo group, suggesting a healthier skin complexion and a smoother and more relaxed skin.
Overall, this study tends to suggest a potential beneficial effect on the emotional and sensory aspects of skin physiology