In the last few years, a new branch of the literature has grown to demonstrate that apart from UV, the visible spectrum of sunlight as well as ambient pollution also induce oxidative stress, cutaneous ageing, and pigmentation. More and more cosmetics products are launched which claim to ward-off damage from these exposome, but no standardized methodologies have till date been developed to substantiate these claims. Using both ex vivo and in vivo models, CIDP proposes to revisit these claims and to propose controlled and calibrated systems as well as evaluation of specific biomarkers to analyse impact of exposome on skin.