09:00 - 10:20
Tue-Hall 2-3A
Hall 2
Podium Session
New findings about the impact of exposome on skin microbiome
Podium 17
Presented by: Aïna Queiroz
Aïna Queiroz 1, Agathe Le Tirant 1, Cécile Gavory 1, Marina Moletta-Denat 2, Martin Baraibar 3, Richard Martin 4
1 Seqens cosmetics, Porcheville
2 Génome et Transcriptome-INRAE Transfert, Auzeville
3 OxiProteomics, Paris
4 Mercurialis Biotech SAS, Rochecorbon
The cosmetics industry is particularly interested in skin microbiota science as well as pollution impact. Considering the permanent contact of air with our skin, it is now essential to also consider the impact of atmospheric microorganisms directly associated with pollutants.
Thanks to this study, the characterization of bacterial populations in aerosols of polluted environments was thus carried out by high-throughput sequencing (16S rRNA) combined with bioinformatics analyses.
After highlighting some differences in the composition of the air and skin microbiota according to the level of pollution, we were able to show significant effects of a topical treatment versus placebo on specific skin parameters. The development of a plant extract derived from buckwheat seeds (Polygonum fagopyrum) applied topically in vivo made it possible to demonstrate a significant action on specific biometric and microbiological parameters at skin level, compared to placebo treatment. We demonstrated the properties of this buckwheat extract applied to a panel of Parisian women naturally subjected to a polluted environment during 1 month of exposure. Significant evolutions were demonstrated both in terms of biometric and biological characteristics (skin tone, oxidation of stratum corneum proteins) associated with an impact on the cutaneous microbiota.
This first candidate to help the microbiota of polluted skin to adapt to this environment led us to consider a new field of research of interest, Expo’biota: “Expo” for exposome, “biota” for skin flora.