15:20 - 16:50
Workshop 4, “Regulation of cytokine production”
Room: ANA Crowne Plaza “Ohtori” Room B
Workshop Session
Chair/s:
Howard A. Young, Osamu Takeuchi
15:20 - 15:40
Mo-WS4-1
Posttranscriptional control of pro-inflammatory cytokine expression by Regnase-1 and Roquin
Osamu Takeuchi
Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan
15:40 - 16:00
Mo-WS4-2
The Dark Side of Interferon-gamma
Howard A. Young1, Heekyong R. Bae1, Deborah L. Hodge1, Guo-Xiang Yang2, Patrick S.C. Leung2, Sathi Babu Chodisetti3, Megan Karwan4, Julio C. Valencia1, Michael Sanford1, John Fenimore1, Seohyun Kim1, Ziaur S.M. Rahman3, Koichi Tsuneyama5, M. Eric Gershwin2
1Cancer and Inflammation Program, National Cancer Institute at Frederick and Leidos, Frederick, United States, 2Division of Rheumatology, Allergy and Clinical Immunology, University of California Davis School of Medicine, Davis, United States, 3Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, United States, 4Laboratory of Animal Science, National Cancer Institute at Frederick, Frederick, United States, 5Department of Pathology and Laboratory Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
16:00 - 16:08
Mo-WS4-3
The importance of cGAMP horizontal transfer in DNA damage-driven inflammation
Genevieve Pepin1, 2, Michael Paul Gantier1, 2
1Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research., Clayton, Australia, 2Department of Molecular and Translational Science, Monash University., Clayton, Australia
16:08 - 16:16
Mo-WS4-4
Malonlyation as a novel inflammatory signal in macrophages
Silvia Galván-Peña1, 2, Steve DeHaro3, George Royal3, Alan Nadin4, Luke A.J O'Neill1, 2
1School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland, 2Immunology Catalyst, GlaxoSmithKline, Stevenage, United Kingdom, 3R&D Target Sciences, GlaxoSmithKline, Stevenage, United Kingdom, 4NCE Molecular Tools Group, GlaxoSmithKline, Stevenage, United Kingdom
16:16 - 16:24
Mo-WS4-5
The protein kinase RIOK3 suppressed MDA5-dependent innate immune response
Ken Takashima1, 2, Hiroyuki Oshiumi3, Hiromi Takaki1, Misako Matsumoto1, Tsukasa Seya1
1Department of Vaccine Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 2Department of Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 3Department of Immunology, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan
16:24 - 16:32
Mo-WS4-6
Functional diversity of zinc-finger antiviral protein isoforms during viral infection
Johannes Schwerk, Frank Soveg, Kerri Thomas, Lauren Aarreberg, Alison Kell, Justin Roby, Michael Gale Jr., Ram Savan
Department of Immunology, University of Washington, Seattle, United States
16:32 - 16:40
Mo-WS4-7
Differential antiviral cytokine responses in human astrocyte cells following infection with different Zika virus strains
Mithun Das, Karla Helbig, Ross O'Shea
Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Bundoora, Australia
16:40 - 16:48
Mo-WS4-8
Intratumoral IRF5 regulates programs an anti-breast tumor immunity resulting in microenvironment that suppresses the suppression of breast tumor growth and metastasis
Dan Li, Betsy Barnes
Northwell Health, Manhasset, United States