13:40 - 15:10
Workshop 3, “Cytokines in skin inflammatory diseases”
Room: ANA Crowne Plaza “Ohtori” Room B
Workshop Session
Chair/s:
Kristin M. Leiferman, Masayuki Amagai
13:40 - 14:00
Mo-WS3-1
Itch and cytokines
Kristin M Leiferman
Department of Dermatology, University of Utah, Salt Lake City, Utah, United States
14:00 - 14:20
Mo-WS3-2
Critical role of CCR7 in peripheral tolerance to CD4+ T cells specific for desmoglein 3 (Dsg3), an autoantigen in pemphigus vulgaris
Masayuki Amagai1, 2, Hisato Iriki1, Hayato Takahashi1
1Department of Dermatology, Keio University School of Medicine, Tokyo, Japan, 2Laboratory for Skin Homeostasis, RIKEN Center for Integrative Medical Sciences, Tsurumi, Japan
14:20 - 14:30
Mo-WS3-3
Pathogenesis of autoreactive Th17 cells is driven by homeostatic cytokines stimulated by commensal microbiota
Shunsuke Chikuma1, Hayato Takahashi2, Masayuki Amagai2, Akihiko Yoshimura1
1Department of Microbiology and Immunology, School of Medicine, Keio University, Tokyo, Japan, 2Department of Dermatology, School of Medicine, Keio University, Tokyo, Japan
14:30 - 14:40
Mo-WS3-4
IL-17E activates M2 macrophages to produce IL-8 and favors the recruitment of neutrophils in psoriatic skin.
Luisa Margarida da Fonte Senra, Romaine Stalder, Wolf-Henning Boehncke, Nicolò Brembilla
Department of Pathology and Immunology, University of Geneva,, Geneva, Switzerland
14:40 - 14:50
Mo-WS3-5
IL-10 derived from regulatory T cells in the skin limits immune responses in percutaneous sensitization
Sho Hanakawa, Akihiko Kitoh, Kenji Kabashima
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
14:50 - 15:00
Mo-WS3-6
Interleukin-31 Modulates Cutaneous Th2 Inflammation
Marlys S Fassett1, 2, K Mark Ansel2
1Department of Dermatology, University of California - San Francisco, San Francisco, United States, 2Department of Microbiology & Immunology, University of California - San Francisco, San Francisco, United States
15:00 - 15:10
Mo-WS3-7
Establishment of a short and predictive mechanistic mouse model to support the development of topical JAK inhibitors
Paola Lovato1, Susanne Knoth Clausen1, Daniel Rodriguez Greve2
1Skin Research, LEO Pharma A/S, Ballerup, Denmark, 2Drug Design, LEO Pharma A/S, Ballerup, Denmark