Inspired by the fascinating structures and intriguing biological activities (Fig. 1), we have investigated the constituents of 5 plants of genus Hypericum, 3 plants of family Myrtaceae, and 1 plant of genus Melicope, which led to the isolation of 258 acylphloroglucinol-terpene derivatives, including 211 new ones and 9 types of novel carbon skeletons. Among them, 6 compounds were chosen as “hot off the press”. These research works of complex absolute configurations, biomimetic syntheses, and biological activities have potential academic value and scientific significance for the research and development of new drugs.
Fig. 1. The biosynthetic pathway of diverse acylphloroglucinol derivatives
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