Punniamurthy N1, Mekala K1, Nair MNB2 , Ramakrishnan N1
murthyvcri@hotmail.com
1EVM Herbal Centre, VUTRC, Tamil Nadu Veterinary and Animal Sciences University, Thanjavur 613 403 Tamil Nadu, India 2 Trans-Disciplinary University, FRLHT, Bangalore, India
Abstract text
Mastitis continues to be a major problem in dairy industry causing severe economic loss to the farmers. A wide variety of antimicrobials have been extensively used through parenteral as well as intramammary route to treat the infectious cause. Ethnoveterinary formulation for mastitis comprising Aloe vera, Curcuma longa and calcium hydroxide has been clinically evaluated and has been found to be successful as a stand-alone treatment mode against mastitis. The phytochemical screening of the formulation revealed the presence of alkaloids, saponins, steroids, carbohydrates, flavonoids, terpenoids, triterpenoids, sterols, emodin and diterpenes. TLC autobiography revealed the antioxidant activity of flavonoids, phenols and glycosides (ICAR Report 2016). Critical analysis of the published literatures provides ample evidence for the antimicrobial, anti-inflammatory and immunomodulating potential of the formulation. It can be concluded that after topical application of the formulation the pharmacologically active components penetrate into the skin and eliminate the infectious agents, effectively reduce the inflammation by suppressing the release of inflammatory mediators, provide analgesic effect, prevent fibrosis and further modulate the immune system of the host [1] resulting in recovery of udder swelling and infection as well as milk production.
References:
1.Kshirsagar, A. D., P. V. Panchal, U. N. Harle, R. K. Nanda and H.M. Shaikh, 2014. Anti-inflammatory and antiarthritic activity of anthraquinone derivatives in rodents. Int. J. Inflam., 12. http://dx.doi.org/10.1155/2014/690596